Strain & heart failure follow-up
Improvement of Strain with SGLT2i therapy in HFrEF & HFmrEF
LASr improvement around 5% (approximately 15% to approximately 20%)
GLS around -2,5% (-9,8% to -12,3%)
FWS around -2% (-15,8% to -17,8%)
To a lesser degree under OMT without SGLT2i
RA strain & HFrEF
Severely reduced RASr — elevated RA & RV filling pressures
LA strain & HFrEF
Severely reduced LASr (3% & 5,9%) in HFrEF
Heart failure
GLS severely reduced (-3,9%), moderately reduced -12,2% (HFimpEF), mildly reduced -14,6% (HFpEF)
