In the end-stage restriction (high E/e’), reduced Strain as an early marker
Involvement primarily of septal segments (scar, reduced strain)
Aneurysms can be seen in advanced disease
Strain shows subclinical involvement for sarcoid heart disease (cut-off GLS -16%; FWS -19,9%)
Worse prognosis GLS >-17,3% & FWS >-20%; LA Strain often reduced (sequence ➜ LV-problem, elevated LA pressures, elevated sPAP ➜ PHT is a marker for bad prognosis)
Diagnostic algorithm ➜ in extracardiac sarcoidosis:
a) normal EF & EKG ➜ GLS>-16,3% or FWS >-19,9% ➜ MRI and/or myocardial biopsy (endomyocardial biopsy is diagnostic)
b) reduced EF, BBB-contraction, VT ➜ exclude CAD ➜ MRI, PET-CT & myocardial biopsy (endomyocardial biopsy is diagnostic)
Sarcoid heart disease, normal EF, basal inferoseptal WMA
Sarcoid heart disease, normal EF, basal inferoseptal WMA
Strain Imaging in sarcoid heart disease, reduction in image quality.
Lateral & anterior not measurable. Infero- & anteroseptal basal & midsegmental regional strain reduction
Strain Imaging in sarcoid heart disease, reduction in image quality.
Lateral & anterior not measurable. Infero- & anteroseptal basal & midsegmental regional strain reduction
Normal LA Strain in Sarcoid Heart Disease
Normal LA Strain in Sarcoid Heart Disease
Sarcoid heart disease with a reduced FWS (-19%), reduced LA strain & reduced GLS -17%, borderline normal EF
Sarcoid heart disease with a reduced FWS (-19%), reduced LA strain & reduced GLS -17%, borderline normal EF
