How to measure LV Strain

  • 3 imaging planes — 4-ChV, 2-ChV, APLAX

  • Focus on the LV (“cut off” the atria)

  • All walls & segments should be visible

  • Older Software ➜ start with APLAX

  • Newer Software ➜ looks for the imaging planes and measures itself (if preferred)

  • CAVE: EKG is still a MUST (P-wave, QRS-complex, T-wave)

  • Similar heart rates required (difference < 5 heartbeats, multiplane as an alternative in AFIB)

  • AVC = Aortic valve closure identification works well (vendor dependent)

  • ROI = region of Interest — thin myocardium ➜ smaller ROI, thick myocardium (e.g., HCMP) ➜ broader ROI (full-wall strain)

  • Sigmoidal septum CAVE — prone to error in regional measurement in this small area (interference of radial & endocardial layers) ➜ don’t measure per se in endocardial strain or discuss limitation in the report, in full-wall strain CAVE

  • ROI: 90% of the myocardium (not the pericardium, not the atrial structures, the LVOT ➜ underestimation; blood speckles ➜ overestimation)

  • Evaluation of plausibility is operator dependent

  • Experience: 50 measurements are recommended to ensure correct measurements

  • Layer specific Strain — longitudinal all myocardial layers act the same during contraction, less Speckles (only 1 layer) has to be used with caution and are probably without any relevant additional information (in the PSAX the LV-mechanics are not the same)

  • Endocardial Strain vs. Full-wall Strain: Endocardial strain is more prone to error in Foreshortening and overall less accurate (less  Speckles)

  • In an automated software, interfere as little as possible, also a not expected regional strain curve should be accepted, otherwise the  bias increases, same holds true for manual changes in tracking. If the measurement is globally subotpimal, don’t use it. Personal tip — get used to your software and your vendor (individual strengths and limitations)

Endocardial normal strain (regional & global)

Endocardial normal strain (regional & global)

Endocardial pathological strain in HFpEF

Endocardial pathological strain in HFpEF

Chan J, Left Ventricular Global Strain Analysis by Two-Dimensional Speckle-Tracking Echocardiography: The Learning Curve. J Am Soc Echocardiogr. 2017 • Voigt et al., 2015

The contents of the website, including the videos, were created without influence from third parties.

The contents of the website, including the videos, were created without influence from third parties.

The Strain Book

Represented by Dr. Martin Altersberger

Contact: heart.lungs.ultrasound@gmail.com

The Strain Book

Represented by Dr. Martin Altersberger

Contact: heart.lungs.ultrasound@gmail.com

© 2026 The Strain Book by Dr. Martin Altersberger. All rights reserved.

© 2026 The Strain Book by Dr. Martin Altersberger. All rights reserved.

© 2026 The Strain Book by Dr. Martin Altersberger. All rights reserved.